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Article

Effect of age and sex on immune checkpoint expression and kinetics in human T cells

4 Nov 2020

Abstract excerpt

BACKGROUND: Immune checkpoints are crucial molecules in maintaining a proper immune balance. Even though age and sex are known to have effects on the immune system, the interplay between age, sex and immune checkpoint expression by T cells is not known. The aim of this study was to determine whether age and sex affect immune checkpoint expression by T cells and if age and sex affect the kinetics of immune...

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PMID: 33292359
DOI: 10.1186/s12979-020-00203-y

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