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Article

Analyzing the Effect of Aging on CD8+ T-Cell Phenotype Using Flow Cytometry.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2015

Shin Min Sun, Kang Insoo

Abstract excerpt

One of the most noticeable changes in T-cell immunity with aging is the expansion of memory CD8+ T cells, with a decline in naïve phenotype T cells that reflects both diminished thymopoiesis and the effects of chronic antigenic stimulation with age. Flow cytometry is a useful tool in evaluating immune cells including the phenotype characteristics of different T-cell subsets. Here, we show flow cytometric methods...

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Identifiers

PMID: 26420713
DOI: 10.1007/978-1-4939-2963-4_10

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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