Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dihydromyricetin promotes longevity and activates the transcription factors FOXO and AOP in Drosophila

3 Dec 2020

Abstract excerpt

lifespan. Dihydromyricetin can also lessen pERK and pAKT signaling, consequently activating FOXO and AOP to modulate longevity. Our results suggested that DHM could be used as an effective compound for anti-aging intervention, which could likely be applied to both mammals and humans.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Natural product bioactivities and synthesis

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 33291074
DOI: 10.18632/aging.202156

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dihydromyricetin promotes longevity and activates the transcription factors FOXO and AOP in DrosophilaPMID 33291074Read ↗

Flavonoids—Natural Gifts to Promote Health and LongevitySemantic proximity Read ↗

The natural flavonoid dihydromyricetin targets senescent cells <i>via</i> PRDX2 and alleviates age-related diseasesSemantic proximity Read ↗

Puerarin extends the lifespan of Drosophila melanogaster by activating autophagySemantic proximity Read ↗

The flavonoid 4,4′-dimethoxychalcone promotes autophagy-dependent longevity across speciesSemantic proximity Read ↗

FOXO3 and Exceptional Longevity: Insights From Hydra to Humans.Semantic proximity Read ↗

A neuroprotective role of Ufmylation through Atg9 in the aging brain of DrosophilaSemantic proximity Read ↗

Pharmaceutical and nutraceutical activation of FOXO3 for healthy longevitySemantic proximity Read ↗

Multiple molecular and cellular mechanisms of the antitumour effect of dihydromyricetin (Review)Semantic proximity Read ↗

Molecular mechanisms of exceptional lifespan increase of Drosophila melanogaster with different genotypes after combinations of pro-longevity interventions.Semantic proximity Read ↗

FOXO/4E-BP Signaling in Drosophila Muscles Regulates Organism-wide Proteostasis during AgingSemantic proximity Read ↗

Finding Ponce de Leon’s Pill: Challenges in Screening for Anti-Aging MoleculesSemantic proximity Read ↗

Identification of dihydromyricetin as a natural DNA methylation inhibitor with rejuvenating activity in human skinSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.