Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lynch Syndrome–Associated Variants and Cancer Rates in an Ancestrally Diverse Biobank

1 Nov 2020

Abstract excerpt

PURPOSE Limited data are available on the prevalence and clinical impact of Lynch syndrome (LS)–associated genomic variants in non-European ancestry populations. We identified and characterized individuals harboring LS-associated variants in the ancestrally diverse Bio Me Biobank in New York City. PATIENTS AND METHODS Exome sequence data from 30,223 adult Bio Me participants were evaluated for pathogenic, likely...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Colorectal Cancer Screening and Detection
Share to Genetic factors in colorectal cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33283134
DOI: 10.1200/po.20.00290

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lynch Syndrome–Associated Variants and Cancer Rates in an Ancestrally Diverse BiobankPMID 33283134Read ↗

Estimating cancer risk in carriers of Lynch syndrome variants in UK BiobankSemantic proximity Read ↗

Estimating cancer risk in carriers of Lynch syndrome variants in UK Biobank.Semantic proximity Read ↗

Impact of population screening for Lynch syndrome insights from the All of Us data.Semantic proximity Read ↗

Genetic Landscape of Lynch Syndrome in a High-Risk Serbian Cohort: Predominance of MLH1 Variants and Implications for Risk-Based Testing.Semantic proximity Read ↗

A Previously Unrecognized Molecular Landscape of Lynch Syndrome in the Mexican PopulationSemantic proximity Read ↗

Cancer risks in Lynch syndrome carriers: a systematic review and meta-analysis.Semantic proximity Read ↗

Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome DatabaseSemantic proximity Read ↗

Incidence and molecular characteristics of deficient mismatch repair conditions across nine different tumors and identification of germline variants involved in Lynch-like syndromeSemantic proximity Read ↗

Lynch syndrome in the general population: low clinical utility of genomic screening for<i>PMS2</i>pathogenic variantsSemantic proximity Read ↗

A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America.Semantic proximity Read ↗

Exome Sequencing Identifies Carriers of the Autosomal Dominant Cancer Predisposition Disorders Beyond Current Practice Guideline Recommendations.Semantic proximity Read ↗

Review article: Lynch Syndrome—a mechanistic and clinical management updateSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.