Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[The Effect of I155T, K156Q, K156E and N186K Mutations in Hemagglutinin on the Virulence and Reproduction of Influenza A/H5N1 Viruses].

Molekuliarnaia biologiia - 1 Jan 2000

Timofeeva T A, Sadykova G K, Lomakina N F, Gambaryan A S, Rudneva I A, Timofeeva E B, Shilov A A, Boravleva E Y, Zhuravleva M M, Ivanov P A, Ryazanova E L, Prilipov A G

Abstract excerpt

The continued circulation of influenza A virus subtype H5 may cause the emergence of new potential pandemic virus variants, which can be transmitted from person to person. The occurrence of such variants is mainly related to mutations in hemagglutinin (HA). Previously we discovered mutations in H5N1 influenza virus hemagglutinin, which contributes to virus immune evasion. The purpose of this work was to study the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chick Embryo
Share to Hemagglutinin Glycoproteins, Influenza Virus

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Influenza A Virus, H5N1 Subtype

Share to Mutation

Share to Orthomyxoviridae Infections

Share to Virulence

Share to Virus Replication

Source

Identifiers

PMID: 33276361
DOI: 10.31857/S0026898420060129

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[The Effect of I155T, K156Q, K156E and N186K Mutations in Hemagglutinin on the Virulence and Reproduction of Influenza A/H5N1 Viruses].PMID 33276361Read ↗

[Mutations in Hemagglutinin and Polymerase Alter the Virulence of Pandemic A(H1N1) Influenza Virus].Semantic proximity Read ↗

Recent H9N2 avian influenza virus lost hemagglutination activity due to a K141N substitution in hemagglutinin.Semantic proximity Read ↗

Novel Mutations Evading Avian Immunity around the Receptor Binding Site of the Clade 2.3.2.1c Hemagglutinin Gene Reduce Viral Thermostability and Mammalian PathogenicitySemantic proximity Read ↗

A single-amino-acid mutation at position 225 in hemagglutinin attenuates H5N6 influenza virus in miceSemantic proximity Read ↗

Investigation of H9N2 avian influenza immune escape mutant that lacks haemagglutination activitySemantic proximity Read ↗

Compensatory Mutations in Avian Influenza H7N1 Hemagglutinin Drive Avian Host Adaptation and Antigenic Drift without Enhancing Replication in Human CellsSemantic proximity Read ↗

Variability of nonpathogenic influenza virus H5N3 under immune pressure.Semantic proximity Read ↗

A single-amino-acid substitution in the HA protein changes the replication and pathogenicity of the 2009 pandemic A (H1N1) influenza viruses in vitro and in vivoSemantic proximity Read ↗

The S190R mutation in the hemagglutinin protein of pandemic H1N1 2009 influenza virus increased its pathogenicity in mice.Semantic proximity Read ↗

[Analysis of the amino acid changes of the hemagglutinin of H5 avian influenza virus].Semantic proximity Read ↗

Substitution Arg140Gly in HA/H7 Reduced the Virulence Highly Pathogenic Avian Influenza Virus H7N1Semantic proximity Read ↗

[Mechanisms of human pathogenicity and adaptability of avian influenza A (H5N1) strains].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.