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So Many Roads: the Multifaceted Regulation of Autophagy Induction

20 Aug 2018

Abstract excerpt

Autophagy is an evolutionary conserved, degradative process from single-cell eukaryotes, such as Saccharomyces cerevisiae, to higher mammals, such as humans. The regulation of autophagy has been elucidated through the combined study of yeast, Caenorhabditis elegans, mice, Drosophila melanogaster, and humans. MTOR, the major negative regulator of autophagy, and activating nutrient kinases, such as 5′-AMP-activated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30126896
DOI: 10.1128/mcb.00303-18

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