Article
Interferon III-related IL28RA variant is associated with rheumatoid arthritis and systemic lupus erythematosus and specific disease sub-phenotypes.
International journal of rheumatic diseases - 1 Jan 2021
Drehmer Manuela Nunes, Castro Gabriel Vaisam, Pereira Ivanio Alves, de Souza Ilíada Rainha, Löfgren Sara Emelie
Abstract excerpt
BACKGROUND: The interferon pathways have been commonly implicated in autoimmune disease development but the identity of the genes involved has not yet been fully clarified. Variation in genes involved in interferon pathways is expected to have a role in the etiology of these diseases. METHODS: The potential association of a polymorphism in the IL28RA gene, involved in these pathways, with susceptibility to...
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