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Article

MAP2K1-Mutated Melanocytic Neoplasms With a SPARK-Like Morphology

1 Dec 2020

Abstract excerpt

ABSTRACT: Specific alterations involving MAPK genes (MAP3K8 fusions, MAP3K3 fusions) have been recently detected in a subgroup of spitzoid neoplasms that seem to constitute a distinctive clinicopathologic group, occur mostly in younger patients (median age 18 years) and present with atypical histologic features associated with frequent homozygous deletion of CDKN2A, qualifying a high proportion of them as Spitz...

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PMID: 33264134
DOI: 10.1097/dad.0000000000001840

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