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New Consensus pattern in Spike CoV-2: potential implications in coagulation process and cell–cell fusion

27 Nov 2020

Abstract excerpt

Coagulopathy and syncytial formation are relevant effects of the SARS-CoV-2 infection, but the underlying molecular mechanisms triggering these processes are not fully elucidated. Here, we identified a potential consensus pattern in the Spike S glycoprotein present within the cytoplasmic domain; this consensus pattern was detected in only 79 out of 561,000 proteins (UniProt bank). Interestingly, the pattern was...

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PMID: 33262894
DOI: 10.1038/s41420-020-00372-1

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