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In silico and in vitro studies reveal complement system drives coagulation cascade in SARS-CoV-2 pathogenesis

1 Jan 2020

Abstract excerpt

The emergence and continued spread of SARS-CoV-2 have resulted in a public health emergency across the globe. The lack of knowledge on the precise mechanism of viral pathogenesis is impeding medical intervention. In this study, we have taken both in silico and in vitro experimental approaches to unravel the mechanism of viral pathogenesis associated with complement and coagulation pathways. Based on the...

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Identifiers

PMID: 33200027
DOI: 10.1016/j.csbj.2020.11.005

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