Article
Genomic and transcriptomic alterations associated with drug vulnerabilities and prognosis in adenocarcinoma at the gastroesophageal junction.
Nature communications - 30 Nov 2020
Lin Yuan, Luo Yingying, Sun Yanxia, Guo Wenjia, Zhao Xuan, Xi Yiyi, Ma Yuling, Shao Mingming, Tan Wen, Gao Ge, Wu Chen, Lin Dongxin
Abstract excerpt
Adenocarcinoma at the gastroesophageal junction (ACGEJ) has dismal clinical outcomes, and there are currently few specific effective therapies because of limited knowledge on its genomic and transcriptomic alterations. The present study investigates genomic and transcriptomic changes in ACGEJ from Chinese patients and analyzes their drug vulnerabilities and associations with the survival time. Here we show that...
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