Correlation of CLEC1B haplotypes with plasma levels of soluble CLEC-2 in healthy individuals.

doi:10.1080/09537104.2020.1849601

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Article

Correlation of CLEC1B haplotypes with plasma levels of soluble CLEC-2 in healthy individuals.

Platelets - 17 Nov 2021

Etemad Mani, Christodoulou Foteini, Weiss Christel, Klüter Harald, Bugert Peter

Abstract excerpt

Binding of podoplanin to the C-type lectin-like receptor 2 (CLEC-2) promotes platelet activation and soluble CLEC-2 (sCLEC-2) is shed from activated platelets. The role of sCLEC-2 in the plasma is unknown. The expression level and plasma concentration of sCLEC-2 could be affected by variants of t...

Topics

Genotype
Haplotypes
Healthy Volunteers
Humans
Lectins, C-Type
Membrane Glycoproteins
Plasma

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