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The many lives of Myc in the pancreatic β-cell

25 Nov 2020

Abstract excerpt

Diabetes results from insufficient numbers of functional pancreatic β-cells. Thus, increasing the number of available functional β-cells ex vivo for transplantation, or regenerating them in situ in diabetic patients, is a major focus of diabetes research. The transcription factor, Myc, discovered decades ago lies at the nexus of most, if not all, known proliferative pathways. Based on this, many studies in the...

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PMID: 33239359
DOI: 10.1074/jbc.rev120.011149

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