Article
High-Dimensional Phenotyping of Human Myeloid-Derived Suppressor Cells/Tumor-Associated Macrophages in Tissue by Mass Cytometry.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021
Ferrant Juliette, Le Gallou Simon, Manson Guillaume, Genebrier Steve, Mourcin Frederic, Tarte Karin, Roussel Mikael
Abstract excerpt
Myeloid-derived suppressor cells (MDSCs) and tumor-associated macrophages (TAMs) are heterogeneous cells that share myeloid markers and are not easily distinguishable in human tumors due to their lack of specific markers. These cells are a major player in the tumor microenvironment and are involved in the prognosis and physiopathology of various tumors. Here is presented a scheme to decipher these cells by mass...
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