Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ADRB1 was identified as a potential biomarker for breast cancer by the co-analysis of tumor mutational burden and immune infiltration.

Aging - 21 Nov 2020

Wang Jia, Zhang Xiaolu, Li Jie, Ma Xiaoran, Feng Fubin, Liu Lijuan, Wu Jibiao, Sun Changgang

Abstract excerpt

Breast cancer (BRCA) has traditionally been considered as having poor immunogenicity and is characterized by relatively low tumor mutational burden (TMB). Improving immunogenicity may improve the response to clinical immunotherapy of BRCA. However, the relationship between TMB, immune infiltration, and prognosis in BRCA remains unclear. We aimed to explore their interrelations and potential biomarkers. In this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Databases, Genetic

Share to Immunotherapy

Share to Lymphocytes, Tumor-Infiltrating

Share to Prognosis

Share to Proportional Hazards Models

Share to Receptors, Adrenergic, beta-1

Source

Open in PubMed Open full text

Identifiers

PMID: 33234738
DOI: 10.18632/aging.104204
PMCID: PMC7835009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ADRB1 was identified as a potential biomarker for breast cancer by the co-analysis of tumor mutational burden and immune infiltration.PMID 33234738Read ↗

ADRB2 is a potential protective gene in breast cancer by regulating tumor immune microenvironmentSemantic proximity Read ↗

The prognostic value of tumor mutation burden (TMB) and its relationship with immune infiltration in breast cancer patients.Semantic proximity Read ↗

MDN1 Mutation Is Associated With High Tumor Mutation Burden and Unfavorable Prognosis in Breast CancerSemantic proximity Read ↗

Identification of the new molecular subtypes related to inflammation in breast cancer.Semantic proximity Read ↗

Integration of bioinformatics and machine learning strategies identifies APM-related gene signatures to predict clinical outcomes and therapeutic responses for breast cancer patientsSemantic proximity Read ↗

A Framework to Predict the Molecular Classification and Prognosis of Breast Cancer Patients and Characterize the Landscape of Immune Cell Infiltration.Semantic proximity Read ↗

Identification of a novel gene signature with DDR and EMT difunctionalities for predicting prognosis, immune activity, and drug response in breast cancerSemantic proximity Read ↗

Identification of a novel immune-related gene signature by single-cell and bulk sequencing for the prediction of the immune landscape and prognosis of breast cancerSemantic proximity Read ↗

The Negative Correlation Between TNBC Mutation Frequency and Immune Function: Is Immune Involvement in Regulating Mutations?Semantic proximity Read ↗

CD1C is associated with Breast Cancer Prognosis and Immune InfiltratesSemantic proximity Read ↗

Integrated analysis identifies TfR1 as a prognostic biomarker which correlates with immune infiltration in breast cancerSemantic proximity Read ↗

A Decision-Aid Model for Predicting Triple-Negative Breast Cancer ICI Response Based on Tumor Mutation BurdenSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.