Article
The Role of Cutaneous Type I IFNs in Autoimmune and Autoinflammatory Diseases
23 Nov 2020
Abstract excerpt
IFNs are well known as mediators of the antimicrobial response but also serve as important immunomodulatory cytokines in autoimmune and autoinflammatory diseases. An increasingly critical role for IFNs in evolution of skin inflammation in these patients has been recognized. IFNs are produced not only by infiltrating immune but also resident skin cells, with increased baseline IFN production priming for...