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Article

RFamide-Related Peptide Neurons Modulate Reproductive Function and Stress Responses.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 20 Jan 2021

Mamgain Asha, Sawyer India L, Timajo David A M, Rizwan Mohammed Z, Evans Maggie C, Ancel Caroline M, Inglis Megan A, Anderson Greg M

Abstract excerpt

RF-amide related peptide 3 (RFRP-3) is a neuropeptide thought to inhibit central regulation of fertility. We investigated whether alterations in RFRP neuronal activity led to changes in puberty onset, fertility, and stress responses, including stress and glucocorticoid-induced suppression of pulsatile luteinizing hormone secretion. We first validated a novel RFRP-Cre mouse line, which we then used in combination...

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Identifiers

PMID: 33219002
DOI: 10.1523/JNEUROSCI.1062-20.2020
PMCID: PMC7821868

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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