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Article

Association of Vitamin D Receptor Polymorphisms with Amyloid-β Transporters Expression and Risk of Mild Cognitive Impairment in a Chilean Cohort.

Journal of Alzheimer's disease : JAD - 1 Jan 2021

Arévalo Nohela B, Castillo-Godoy Daniela P, Espinoza-Fuenzalida Italo, Rogers Nicole K, Farias Gonzalo, Delgado Carolina, Henriquez Mauricio, Herrera Luisa, Behrens María Isabel, SanMartín Carol D

Abstract excerpt

BACKGROUND: Amyloid-β peptide (Aβ) deposition in Alzheimer's disease (AD) is due to an imbalance in its production/clearance rate. Aβ is transported across the blood-brain barrier by LRP1 and P-gp as efflux transporters and RAGE as influx transporter. Vitamin D deficit and polymorphisms of the vitamin D receptor (VDR) gene are associated with high prevalence of mild cognitive impairment (MCI) and AD. Further,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33216035
DOI: 10.3233/JAD-201031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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