Article
Crosstalk Between Gut Microflora and Vitamin D Receptor SNPs Are Associated with the Risk of Amnestic Mild Cognitive Impairment in a Chinese Elderly Population.
Journal of Alzheimer's disease : JAD - 1 Jan 2022
Zhang Kaixia, Ma Xiaoying, Zhang Rui, Liu Zanchao, Jiang Lei, Qin Yushi, Zhang Di, Tian Pei, Gao ZhaoYu, Zhang Nan, Shi Zhongli, Xu Shunjiang
Abstract excerpt
BACKGROUND: The interactions between environmental factors and genetic variants have been implicated in the pathogenesis of Alzheimer's disease (AD). The altered gut microbiota (GM) and vitamin D deficiency are closely associated with the higher risk of AD. OBJECTIVE: This study was performed to evaluate whether the crosstalk between GM and single nucleotide polymorphisms (SNPs) of vitamin D receptor (VDR) or...
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