Article
Vitamin D in Alzheimer's Disease: Low Levels in Cerebrospinal Fluid Despite Normal Amounts in Serum.
Journal of Alzheimer's disease : JAD - 1 Jan 2022
Soares Jelena Zugic, Valeur Jørgen, Šaltytė Benth Jūratė, Knapskog Anne-Brita, Selbæk Geir, Arefi Golchin, Gilfillan Gregor D, Tollisen Anita, Bogdanovic Nenad, Pettersen Renate
Abstract excerpt
BACKGROUND: Vitamin D insufficiency has been suggested as a dementia risk factor. OBJECTIVE: In this cross-sectional, explorative study we investigated whether levels of vitamin D in cerebrospinal fluid (CSF) are lower in patients with positive biomarkers of Alzheimer's disease (AD) compared to cognitively healthy controls and whether polymorphisms of the vitamin D receptor (VDR) gene, FokI, BsmI, ApaI, and TaqI,...
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