Article
Lack of TMEM230 mutations in patients with familial and sporadic Parkinson's disease in a Taiwanese population.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Oct 2017
Fan Tian-Sin, Lin Chin-Hsien, Lin Hang-I, Chen Meng-Ling, Wu Ruey-Meei
Abstract excerpt
Mutations in transmembrane protein 230 (TMEM230) have recently been reported to be associated with Parkinson's disease (PD) in a North American population. A highly prevalent mutation, c.550_552delTAGinsCCCGGG (p.*184ProGlyext*5) was found in 3.1% of Chinese familial PD patients. However, subsequent studies failed to replicate these findings in different populations. Our objective was to confirm the role of this...
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