Shape of population interfaces as an indicator of mutational instability in coexisting cell populations.

doi:10.1088/1478-3975/abb2dd

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Article

Shape of population interfaces as an indicator of mutational instability in coexisting cell populations.

Physical biology - 19 Nov 2020

Castillo Clarisa E, Lavrentovich Maxim O

Abstract excerpt

Cellular populations such as avascular tumors and microbial biofilms may 'invade' or grow into surrounding populations. The invading population is often comprised of a heterogeneous mixture of cells with varying growth rates. The population may also exhibit mutational instabilities, such as a heavy deleterious mutation load in a cancerous growth. We study the dynamics of a heterogeneous, mutating population...

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PMID: 33210619
DOI: 10.1088/1478-3975/abb2dd

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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