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The cytoplasmic loops of AgrC contribute to the quorum-sensing activity of Staphylococcus aureus

17 Nov 2020

Abstract excerpt

In Staphylococcus aureus, the accessory gene regulator (agr) quorum-sensing system is thought to play an important role in biofilm formation. The histidine kinase AgrC is one of the agr system components and activated by the self-generated auto-inducing peptide (AIP), which is released continuously into the extracellular environment during bacterial growth. The extracellular loops (Extra-loops) of AgrC are...

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PMID: 33201435
DOI: 10.1007/s12275-021-0274-x

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