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The Mechanisms and therapeutic effects of granulocyte colony-stimulating factor in reproduction

26 May 2025

Abstract excerpt

Granulocyte colony-stimulating factor (G-CSF) is a hematopoietic cytokine that is primarily secreted by monocytes or macrophages and has traditionally been recognized for its role in stimulating the proliferation and differentiation of neutrophils. Recent research has revealed the presence of G-CSF in non-hematopoietic cells such as vascular endothelial cells, placental cells, and trophoblast cells. This...

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PMID: 40420179
DOI: 10.1186/s12958-025-01414-y

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