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Article

The association of circulating kynurenine, a tryptophan metabolite, with frailty in older adults.

Aging - 13 Nov 2020

Jang Il-Young, Park Jin Hoon, Kim Jeoung Hee, Lee Seungjoo, Lee Eunju, Lee Jin Young, Park So Jeong, Kim Da Ae, Hamrick Mark W, Kim Beom-Jun

Abstract excerpt

Despite the accumulating evidence from in vitro and animal experiments supporting the role of kynurenine (a tryptophan metabolite) in a number of degenerative age-related changes, the relationship between kynurenine and frailty in older adults is not well understood. We collected blood samples from 73 participants who underwent a comprehensive geriatric assessment, measuring kynurenine levels using liquid...

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Identifiers

PMID: 33188590
DOI: 10.18632/aging.104179
PMCID: PMC11623974

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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