Article
Frailty defined by deficit accumulation and geriatric medicine defined by frailty.
Clinics in geriatric medicine - 1 Feb 2011
Rockwood Kenneth, Mitnitski Arnold
Abstract excerpt
As nonreplicative cells age, they commonly accumulate subcellular deficits that can compromise function. As people age, they too experience problems that can accumulate. As deficits (symptoms, signs, illnesses, disabilities) accumulate, people become more susceptible to adverse health outcomes, including worse health and even death. This state of increased risk of adverse health outcomes is indistinguishable from...
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