Article
Functional analysis of the brain natriuretic peptide gene for high-altitude adaptation in Tibetan pigs.
Gene - 5 Feb 2021
Tian Xiaolong, Ma Jun, Wu Yijing, Zhang Pan, Li Qinggang, Zhang Hao, Wu Changxin
Abstract excerpt
High-altitude adaptation in Tibetan pigs (TP) is associated with positively-selected genes. The brain natriuretic peptide (BNP) gene is critical in the regulation of cardiovascular homeostasis and energy metabolism. The present study was conducted to identify the function of BNP for high-altitude adaptations in TP. RT-qPCR and western blotting results indicated that BNP expression could be upregulated when the...
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