Article
Genetic Adaptations of the Tibetan Pig to High-Altitude Hypoxia on the Qinghai-Tibet Plateau.
International journal of molecular sciences - 21 Oct 2024
Yang Yanan, Yuan Haonan, Yao Boyuan, Zhao Shengguo, Wang Xinrong, Xu Linna, Zhang Lingyun
Abstract excerpt
The Tibetan Plateau's distinctive high-altitude environment, marked by extreme cold and reduced oxygen levels, presents considerable survival challenges for both humans and mammals. Natural selection has led to the accumulation of adaptive mutations in Tibetan pigs, enabling them to develop distinctive adaptive phenotypes. Here, we aim to uncover the genetic mechanisms underlying the adaptation of Tibetan pigs to...
Topics
- Animals
- Tibet
- Altitude
- Swine
- Adaptation, Physiological
- Selection, Genetic
- Polymorphism, Single Nucleotide
- Whole Genome Sequencing
- Hypoxia
- Acclimatization
- Phenotype