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Article

microRNA-96 promotes occurrence and progression of colorectal cancer via regulation of the AMPKα2-FTO-m6A/MYC axis

12 Nov 2020

Abstract excerpt

BACKGROUND: Colorectal cancer (CRC) is one of the frequently occurred malignancies in the world. To date, several onco-microRNAs (miRNAs or miRs), including miR-96, have been identified in the pathogenesis of CRC. In the present study, we aimed to corroborate the oncogenic effect of miR-96 on CRC and to identify the specific mechanisms related to AMPKα2/FTO/m6A/MYC. METHODS: RT-qPCR and Western blot analysis were...

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PMID: 33183350
DOI: 10.1186/s13046-020-01731-7

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