Article
Association of Interleukin-12B Polymorphism and Serum Level of Interleukin-12 in a Sample of Egyptian Patients with Rheumatoid Arthritis.
The Egyptian journal of immunology - 1 Jan 2020
El-Hakeim Eman H, Abd Elhameed Zeinab A, Nouby Fatma H, Abdel Razek Mohamed R, El-Moneum Omnia A, Goma Samar H
Abstract excerpt
Rheumatoid arthritis (RA) is one of the common autoimmune diseases, which affected by genetic and environmental factors. IL-12 is important cytokine that play an effective role in the inflammatory reaction of RA. It regulates the balance between Th1 and Th2 cells. Gene polymorphism of cytokines may predispose to susceptibility and severity of RA. To assess the association between single nucleotide polymorphism...
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