Article
Association GSTT1, GSTM1 and GSTP1 (Ile105Val) genetic polymorphisms in mothers with risk of congenital malformations in their children in Western Siberia: a case-control study.
Prenatal diagnosis - 1 Nov 2013
Gordeeva Lyudmila A, Voronina Elena N, Sokolova Ekaterina A, Ermolenko Natalia A, Gareeva Julia V, Sutulina Irina M, Simonova Tatiana A, Filipenko Maxim L, Glushkov Andrej N
Abstract excerpt
OBJECTIVE: Polymorphisms of glutathione S-transferase (GST) genes in mothers may be involved in teratogenesis in their offspring. This study aims to investigate the association of GST genes (T1, M1 and P1) with the risk of having children with congenital malformations (CMs) in residents of the West Siberian region of Russia. METHOD: We studied 235 women with offspring's with CMs, and 273 women with one or more...
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