Article
Phenotypic Tracking of Antibiotic Resistance Spread via Transformation from Environment to Clinic by Reverse D2O Single-Cell Raman Probing.
Analytical chemistry - 1 Dec 2020
Li Hong-Zhe, Zhang DanDan, Yang Kai, An Xin-Li, Pu Qiang, Lin Shao-Min, Su Jian-Qiang, Cui Li
Abstract excerpt
The rapid spread of antibiotic resistance threatens our fight against bacterial infections. Environments are an abundant reservoir of potentially transferable resistance to pathogens. However, the trajectory of antibiotic resistance genes (ARGs) spreading from environment to clinic and the associated risk remain poorly understood. Here, single-cell Raman spectroscopy combined with reverse D2O labeling...
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