Article

Measuring Microbial Community-Wide Antibiotic Resistance Propagation via Natural Transformation in the Human Gut Microbiome

2024-11-29

Abstract excerpt

1) This work explored the role of natural transformation – a mechanism by which bacteria uptake and express extracellular genes - in driving antibiotic resistance propagation in the human gut microbiome. The model extracellular antibiotic resistance gene (eARG) – a plasmid containing a kanamycin resistance ( kanR ) gene and a green fluorescence protein (GFP) gene – was dosed into pooled and homogenized human stoo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d1f89be7-f852-59b8-a960-25e1546a0940
DOI: 10.1101/2024.11.26.625464

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Measuring Microbial Community-Wide Antibiotic Resistance Propagation via Natural Transformation in the Human Gut MicrobiomeDOI 10.1101/2024.11.26.625464Read

Evaluation of Gentamicin Exposure Effects on Human gut Microbiota using the Simulator of Human Intestinal Microbial Ecosystem (SHIME)Semantic proximity Read

A systematic review of enteric pathogens and antibiotic resistance genes in outdoor urban aerosolsSemantic proximity Read

Antibiotic Treatment Drives the Diversification of the Human Gut ResistomeSemantic proximity Read

Amoxicillin exposure significantly increases the population and virulence of antibiotic-resistant Klebsiella pathogen in the simulated human intestinal microbiotaSemantic proximity Read

In vitro demonstration of broad host range mobile genetic elements transferring antibiotic resistance from the human microbiomeSemantic proximity Read

Horizontal gene transfer facilitates the spread of extracellular antibiotic resistance genes in soilSemantic proximity Read

Expansion and persistence of antibiotic-specific resistance genes following antibiotic treatmentSemantic proximity Read

Non-antibiotic pharmaceuticals enhance the transmission of exogenous antibiotic resistance genes through bacterial transformationSemantic proximity Read

Horizontal transfer of antibiotic resistance genes in the human gut microbiomeSemantic proximity Read

Widespread transfer of mobile antibiotic resistance genes within individual gut microbiomes revealed through bacterial Hi-CSemantic proximity Read