Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis

9 Nov 2020

Abstract excerpt

Significance Kinetoplastids is a group of flagellated unicellular eukaryotic parasites including human pathogens, such as Trypanosoma cruzi and Leishmania spp., etiologic agents of Chagas disease and leishmaniasis. They are potentially lethal, affecting more than 20 million people worldwide. Therapeutic strategies are extremely limited and highly toxic. The finding of new molecular targets represents one venue...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biochemical and Molecular Research
Share to Research on Leishmaniasis Studies
Share to Trypanosoma species research and implications

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33168716
DOI: 10.1073/pnas.2011301117

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesisPMID 33168716Read ↗

Structure of the full kinetoplastids mitoribosome and insight on its large subunit maturationSemantic proximity Read ↗

Identification and Validation of Toxoplasma gondii Mitoribosomal Large Subunit ComponentsSemantic proximity Read ↗

An Update on Mitochondrial Ribosome Biology: The Plant Mitoribosome in the Spotlight.Semantic proximity Read ↗

Divergent Mitochondrial Ribosomes in Unicellular Parasitic Protozoans.Semantic proximity Read ↗

Parasite powerhouse: A review of the Toxoplasma gondii mitochondrionSemantic proximity Read ↗

Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomesSemantic proximity Read ↗

Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian HostsSemantic proximity Read ↗

Trypanosomatids: Odd Organisms, Devastating DiseasesSemantic proximity Read ↗

Structural differences in translation initiation between pathogenic trypanosomatids and their mammalian hostsSemantic proximity Read ↗

Trypanosoma brucei L11 Is Essential to Ribosome Biogenesis and Interacts with the Kinetoplastid-Specific Proteins P34 and P37Semantic proximity Read ↗

The Diseased Mitoribosome.Semantic proximity Read ↗

Genetic ablation of the mitochondrial ribosome in <i>Plasmodium falciparum</i> sensitizes the human malaria parasite to antimalarial drugs targeting mitochondrial functionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.