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Article

Deep brain stimulation by optimized stimulators in a phenotypic model of dystonia: Effects of different frequencies.

Neurobiology of disease - 1 Jan 2021

Paap Maria, Perl Stefanie, Lüttig Anika, Plocksties Franz, Niemann Christoph, Timmermann Dirk, Bahls Christian, van Rienen Ursula, Franz Denise, Zwar Monique, Rohde Marco, Köhling Rüdiger, Richter Angelika

Abstract excerpt

Deep brain stimulation (DBS) of the globus pallidus internus (GPi, entopeduncular nucleus, EPN, in rodents) has become important for the treatment of generalized dystonia, a severe and often intractable movement disorder. It is unclear if lower frequencies of GPi-DBS or stimulations of the subthalamic nucleus (STN) are of advantage. In the present study, the main objective was to examined the effects of bilateral...

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PMID: 33166698
DOI: 10.1016/j.nbd.2020.105163

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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