Article
Development and evaluation of a national reference panel of HIV-1 protease and reverse transcriptase drug-resistance mutations for HIV-1 genotypic resistance assays in China.
Molecular diagnosis & therapy - 1 Feb 2010
Xu Sihong, Li Jingyun, Bao Zuoyi, Xing Hui, Zhong Ping, Li Hanping, Zhou Haiwei, Li Xinping, Wu Sharon, Song Aijing, Li Xiuhua, Nie Jianhui, Wang Youchun
Abstract excerpt
BACKGROUND: Transmission of antiretroviral drug-resistant strains of HIV-1 has a major impact on the success of HIV treatment regimens in most countries where antiretroviral therapy (ART) is available. It is now recommended that HIV-1 drug resistance be monitored in order to recommend appropriate therapy for infected ART-naïve individuals, or when choosing a new regimen for those patients not responding to ART....
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