Article
The role of parental and grandparental epigenetic alterations in familial cancer risk.
Cancer research - 15 Nov 2008
Fleming Jessica L, Huang Tim H-M, Toland Amanda Ewart
Abstract excerpt
Epigenetic alterations of the genome such as DNA promoter methylation and chromatin remodeling play an important role in tumorigenesis. These modifications take place throughout development with subsequent events occurring later in adulthood. Recent studies, however, suggest that some epigenetic...
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