Article
Increased Hydrostatic Pressure Promotes Primary M1 Reaction and Secondary M2 Polarization in Macrophages.
Frontiers in immunology - 1 Jan 2020
Wang Bo, Kasper Maren, Laffer Björn, Meyer Zu Hörste Gerd, Wasmuth Susanne, Busch Martin, Jalilvand Tida Viola, Thanos Solon, Heiligenhaus Arnd, Bauer Dirk, Heinz Carsten
Abstract excerpt
Patients with chronic anterior uveitis are at particularly high risk of developing secondary glaucoma when corticosteroids [e.g., dexamethasone (Dex)] are used or when inflammatory activity has regressed. Macrophage migration into the eye increases when secondary glaucoma develops and may play an important role in the development of secondary glaucoma. Our aim was to evaluate in vitro if increased hydrostatic...
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