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Article

SMN protein promotes membrane compartmentalization of ribosomal protein S6 transcript in human fibroblasts

4 Nov 2020

Abstract excerpt

Alterations of RNA homeostasis can lead to severe pathological conditions. The Survival of Motor Neuron (SMN) protein, which is reduced in Spinal Muscular Atrophy, impacts critical aspects of the RNA life cycle, such as splicing, trafficking, and translation. Increasing evidence points to a potential role of SMN in ribosome biogenesis. Our previous study revealed that SMN promotes membrane-bound ribosomal...

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PMID: 33149163
DOI: 10.1038/s41598-020-76174-3

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SMN protein promotes membrane compartmentalization of ribosomal protein S6 transcript in human fibroblastsPMID 33149163Read ↗

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