Article
Technical advance: The use of tree shrews as a model of pulmonary fibrosis.
PloS one - 1 Jan 2020
Larson-Casey Jennifer L, He Chao, Che Pulin, Wang Meimei, Cai Guoqiang, Kim Young-Il, El Hamdaoui Mustapha, Grytz Rafael, Ding Qiang, Carter A Brent
Abstract excerpt
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive disease with a high morbidity and mortality. Some of the mechanisms of fibrosis development have been described using rodent models; however, the relevance of findings in these animal models is difficult to assess. New innovative models are needed that closely mimic IPF disease pathology. METHODS: To overcome this unmet need of...
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