Article
Relative contributions of lipooligosaccharide inner and outer core modifications to nontypeable Haemophilus influenzae pathogenesis.
Infection and immunity - 1 Nov 2013
Morey Pau, Viadas Cristina, Euba Begoña, Hood Derek W, Barberán Montserrat, Gil Carmen, Grilló María Jesús, Bengoechea José Antonio, Garmendia Junkal
Abstract excerpt
Nontypeable Haemophilus influenzae (NTHi) is a frequent commensal of the human nasopharynx that causes opportunistic infection in immunocompromised individuals. Existing evidence associates lipooligosaccharide (LOS) with disease, but the specific and relative contributions of NTHi LOS modifications to virulence properties of the bacterium have not been comprehensively addressed. Using NTHi strain 375, an isolate...
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