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Article

XIAP BIR domain suppresses miR-200a expression and subsequently promotes EGFR protein translation and anchorage-independent growth of bladder cancer cell.

Journal of hematology & oncology - 5 Jan 2017

Huang Chao, Zeng Xingruo, Jiang Guosong, Liao Xin, Liu Claire, Li Jingxia, Jin Honglei, Zhu Junlan, Sun Hong, Wu Xue-Ru, Huang Chuanshu

Abstract excerpt

BACKGROUND: The X-linked inhibitor of apoptosis protein (XIAP) is a well-known potent apoptosis suppressor and also participates in cancer cell biological behaviors, therefore attracting great attentions as a potential antineoplastic therapeutic target for past years. Anti-IAP therapy is reported to be closely related to epidermal growth factor receptor (EGFR) expression level. However, whether and how XIAP...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28057023
DOI: 10.1186/s13045-016-0376-9
PMCID: PMC5217641

Genes

XIAP
EGFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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XIAP BIR domain suppresses miR-200a expression and subsequently promotes EGFR protein translation and anchorage-independent growth of bladder cancer cell.PMID 28057023Read ↗

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