Article
Retbindin: A riboflavin Binding Protein, Is Critical for Photoreceptor Homeostasis and Survival in Models of Retinal Degeneration.
International journal of molecular sciences - 29 Oct 2020
Genc Ayse M, Makia Mustafa S, Sinha Tirthankar, Conley Shannon M, Al-Ubaidi Muayyad R, Naash Muna I
Abstract excerpt
The large number of inherited retinal disease genes (IRD), including the photopigment rhodopsin and the photoreceptor outer segment (OS) structural component peripherin 2 (PRPH2), has prompted interest in identifying common cellular mechanisms involved in degeneration. Although metabolic dysregulation has been shown to play an important role in the progression of the disease etiology, identifying a common...
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