Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Development, phenotypes of immune cells in BTBR T+Itpr3tf/J mice.

Cellular immunology - 1 Dec 2020

Uddin Mohammad Nizam, Yao Yunyi, Manley Kevin, Lawrence David A

Abstract excerpt

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition that is characterized by a lack of social interaction, decreased verbal and non-verbal communication skills, and stereotyped repetitive behavior. There is strong evidence that a dysregulated immune response may influence neurodevelopment and thus may have a role in the development of ASD. This study focuses on the characterization of immune...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autism Spectrum Disorder
Share to Autistic Disorder
Share to CD8-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Forkhead Transcription Factors

Share to GATA3 Transcription Factor

Share to Inositol 1,4,5-Trisphosphate Receptors

Share to Mice, Inbred Strains

Share to T-Lymphocytes, Regulatory

Source

Identifiers

PMID: 33137646
DOI: 10.1016/j.cellimm.2020.104223

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Development, phenotypes of immune cells in BTBR T+Itpr3tf/J mice.PMID 33137646Read ↗

Altered meningeal immunity contributing to the autism-like behavior of BTBR <i>T</i> <sup>+</sup> <i> Itpr3 <sup>tf</sup> </i> /J miceSemantic proximity Read ↗

Inflammatory profiles in the BTBR mouse: how relevant are they to autism spectrum disorders?Semantic proximity Read ↗

The BTBR T+ tf/J mouse model for autism spectrum disorders-in search of biomarkers.Semantic proximity Read ↗

Treg Cells Modulate Neuroinflammation and Behavioral Deficits in Autism: Evidence From MR-Based Genetic Analyses and Experimental Models.Semantic proximity Read ↗

5-aminoisoquinolinone attenuates social behavior deficits and immune abnormalities in the BTBR T+ Itpr3tf/J mouse model for autism.Semantic proximity Read ↗

Characterization of immune cell phenotypes in adults with autism spectrum disorders.Semantic proximity Read ↗

Early postnatal activation of A2ARs alleviates social deficits by attenuating the abnormal infiltration of peripheral neutrophils in the BTBR T + Itpr3 tf /J mouse model of autismSemantic proximity Read ↗

Maternal immune activation and strain specific interactions in the development of autism-like behaviors in mice.Semantic proximity Read ↗

TH1/Treg ratio may be a marker of autism in children with immune dysfunctionSemantic proximity Read ↗

Sex-related alterations of gut microbiota composition in the BTBR mouse model of autism spectrum disorder.Semantic proximity Read ↗

Exaggerated responses to stress in the BTBR T+tf/J mouse: an unusual behavioral phenotype.Semantic proximity Read ↗

Comorbid epilepsy in autism spectrum disorder: Implications of postnatal inflammation for brain excitability.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.