Two Nimrod receptors, NimC1 and Eater, synergistically contribute to bacterial phagocytosis in Drosophila melanogaster

Abstract excerpt

Eater and NimC1 are transmembrane receptors of the Drosophila Nimrod family, specifically expressed in haemocytes, the insect blood cells. Previous ex vivo and in vivo RNA i studies have pointed to their role in the phagocytosis of bacteria. Here, we have created a novel NimC1 null mutant to re‐evaluate the role of NimC1, alone or in combination with Eater, in the cellular immune response. We show that NimC1...

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