Article
Dangerous liaisons: the apoptotic engulfment receptor CED-1 links innate immunity to the unfolded protein response.
Developmental cell - 1 Jul 2008
Lamitina Todd, Cherry Sara
Abstract excerpt
In this issue of Developmental Cell, Haskins et al. describe a molecular link between an apoptotic cell receptor, a branch of the unfolded protein response, and innate immunity. The finding that the plasma membrane phagocytic receptor CED-1 promotes the expression of unfolded response genes suggests a novel regulatory mechanism for the control of this primitive immune system that may couple the presence of...
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