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Article

Drosophila eiger mutants are sensitive to extracellular pathogens.

PLoS pathogens - 1 Mar 2007

Schneider David S, Ayres Janelle S, Brandt Stephanie M, Costa Alexandre, Dionne Marc S, Gordon Michael D, Mabery Eric M, Moule Madeleine G, Pham Linh N, Shirasu-Hiza Mimi M

Abstract excerpt

We showed previously that eiger, the Drosophila tumor necrosis factor homolog, contributes to the pathology induced by infection with Salmonella typhimurium. We were curious whether eiger is always detrimental in the context of infection or if it plays a role in fighting some types of microbes. We challenged wild-type and eiger mutant flies with a collection of facultative intracellular and extracellular...

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Identifiers

PMID: 17381241
DOI: 10.1371/journal.ppat.0030041
PMCID: PMC1829408

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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