Article
Identification of pan-cancer Ras pathway activation with deep learning.
Briefings in bioinformatics - 20 Jul 2021
Li Xiangtao, Li Shaochuan, Wang Yunhe, Zhang Shixiong, Wong Ka-Chun
Abstract excerpt
The identification of hidden responders is often an essential challenge in precision oncology. A recent attempt based on machine learning has been proposed for classifying aberrant pathway activity from multiomic cancer data. However, we note several critical limitations there, such as high-dimensionality, data sparsity and model performance. Given the central importance and broad impact of precision oncology, we...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.