Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Vaccinia Virus Activation and Antagonism of Cytosolic DNA Sensing

1 Oct 2020

Abstract excerpt

Cells express multiple molecules aimed at detecting incoming virus and infection. Recognition of virus infection leads to the production of cytokines, chemokines and restriction factors that limit virus replication and activate an adaptive immune response offering long-term protection. Recognition of cytosolic DNA has become a central immune sensing mechanism involved in infection, autoinflammation, and cancer...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Herpesvirus Infections and Treatments
Share to Poxvirus research and outbreaks
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33117352
DOI: 10.3389/fimmu.2020.568412

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Vaccinia Virus Activation and Antagonism of Cytosolic DNA SensingPMID 33117352Read ↗

Intracellular sensing of viral genomes and viral evasionSemantic proximity Read ↗

Evasion of Intracellular DNA Sensing by Human HerpesvirusesSemantic proximity Read ↗

Innate Sensing of DNA Virus GenomesSemantic proximity Read ↗

A Replication‐Defective Myxoma Virus Inducing Pro‐Inflammatory Responses as Monotherapy and an Adjuvant to Chemo‐ and DC Immuno‐Therapy for Ovarian CancerSemantic proximity Read ↗

How does Vaccinia virus inhibit the detection of cytosolic DNA by the innate immune system?Semantic proximity Read ↗

The unique immune evasion mechanisms of the mpox virus and their implication for developing new vaccines and immunotherapiesSemantic proximity Read ↗

The Emerging Role of Nuclear Viral DNA SensorsSemantic proximity Read ↗

Cellular Sensing of Viral DNA and Viral Evasion MechanismsSemantic proximity Read ↗

Viral double-stranded RNAs from vaccinia virus early or intermediate gene transcripts possess PKR activating function, resulting in NF-kappaB activation, when the K1 protein is absent or mutated.Semantic proximity Read ↗

Temporal expression classes and functions of vaccinia virus and mpox (monkeypox) virus genesSemantic proximity Read ↗

Replicating poxviruses for human cancer therapySemantic proximity Read ↗

Protoparvovirus Cell EntrySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.