Article
A Parainfluenza Virus Vector Expressing the Respiratory Syncytial Virus (RSV) Prefusion F Protein Is More Effective than RSV for Boosting a Primary Immunization with RSV.
Journal of virology - 22 Dec 2020
Liang Bo, Matsuoka Yumiko, Le Nouën Cyril, Liu Xueqiao, Herbert Richard, Swerczek Joanna, Santos Celia, Paneru Monica, Collins Peter L, Buchholz Ursula J, Munir Shirin
Abstract excerpt
Live-attenuated pediatric vaccines for intranasal administration are being developed for human respiratory syncytial virus (RSV), an important worldwide pediatric respiratory pathogen that lacks a licensed vaccine or suitable antiviral drug. We evaluated a prime-boost strategy in which primary immunization with RSV was boosted by secondary immunization with RSV or with a chimeric recombinant bovine/human...
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